WebSep 6, 2024 · CONKAT-seq (co-occurrence network analysis of targeted sequences) is used to detect captured BGCs, evaluate their novelty and determine their physical … WebSep 6, 2024 · Europe PMC is an archive of life sciences journal literature.
GitHub - brady-lab-rockefeller/BGCs_in_rare_metagenomic_DNA
WebCONKAT-seq allows scalable exploration of largely untapped biosynthetic diversity across multiple soils, and can guide the discovery of novel secondary metabolites from rare … WebAug 26, 2024 · CONKAT-seq allows scalable exploration of largely untapped biosynthetic diversity across multiple soils, and can guide the discovery of novel secondary … rose blue for you
Uncovering the biosynthetic potential of rare metagenomic DNA …
WebOur solution simultaneously captures large numbers of BGCs by cloning the genomes of a strain collection in a large-insert library and uses the CONKAT-seq (co-occurrence network analysis of... WebApr 6, 2024 · Here, the authors improve the CONKAT-seq strategy by simultaneously capturing the BCGs into a single large insert library and demonstrate its ability to discover natural products with new ... WebWe show that a single soil sample can contain more than a thousand uncharacterized biosynthetic gene clusters, most of which originate from low frequency genomes which are practically inaccessible through untargeted sequencing. CONKAT-seq allows scalable exploration of largely untapped biosynthetic diversity across multiple soils, and can guide ... rose boland red wing mn